Companies have to constantly adopt and adjust themselves to the changing market requirements, changing customer needs and expectations, new technologies and the changing environment. In the pharmaceutical market the patent protection of innovations expire after an average time of ten years – therefore research-oriented companies have to re-invent themselves every ten years accordingly. New products, manufacturing technologies and healthcare solutions represent the core of any innovation strategy. Or expressed in a different way – if companies fail to constantly re-invent themselves, they might lose their market position, customer base, or even disappear as entity. Today, General Electric is the only company remaining as such in the Dow Jones Industrial Index since it was first published in 1896.